Journal of Inflammatory Diseases
Volume:24 Issue: 3, 2020

 Exercise is one of the methods affecting cardiovascular adaptation, but its cellular and molecular pathways and mechanisms are unknown. T-Box Transcription Factor 5 (TBX5) gene seems to be one of the factors involved in regulating cardiac hypertrophy.

 The aim of this study was to investigate the effect of an 8-week exercise program with different intensities on the expression of TBX5 gene in the heart of male Wistar rats.

 In this experimental study, 24 male adult Wistar rats were divided into three groups of High Intensity Training (HIT), Low Intensity Training and (LIT) and control. Training groups performed the exercise program for 8 weeks, 5 sessions per week. The exercise program for the HIT group consists of running on a treadmill with five 8-min intervals at 85-90% VO2 max intensity divided into 2-min intervals at 50-60% VO2 max intensity, while for the LIT group it was included five 8-min intervals with 50-60% VO2 max intensity divided into 2-min intervals with 45% -50% VO2 max intensity. The control group performed no exercise. The real-time Polymerase Chain Reaction (PCR) analysis was used to measure the expression level of TBX5 gene. The collected data were analyzed by one-way ANOVA and Tukey’s post hoc test.

 The heart weight (P≤0.001 and P=0.004), heart-weight to body-weight ratio (P≤0.0001 and P=0.001), and left ventricular wall thickness were significantly higher in the HIT and LIT groups than in the control group (P≤0.0001 and P=0.38 ). The left ventricular wall thickness in the HIT group was significantly higher than in the LIT group (P=0.001). The TBX5 expression in the two training groups were not significantly different from that of control group (P=0.11).

 It seems that more intensive exercise can have more significant effects on cardiac hypertrophy than less intensive exercise.

 Assertiveness is one of the most important skills needed by nurses to reduce interpersonal conflict and build an effective teamwork in complex hospital environments. 

 The aim of this study was to determine the effect of an assertiveness training program on nurses’ aggressive and adaptive assertiveness. 

 In this interventional study, participants were 64 nurses working in hospitals of Abhar city in Iran, randomly divided into two groups of intervention (n=32) and control (n=32). Assertive training program was presented as a two-day training workshop (10 hours) to the intervention group, while the control group received no training. Thompson and Burnham’s Adaptive and Aggressive Assertiveness Scale were completed by the participants in both groups at baseline, immediately, one and three months after the intervention. After collecting the data, Friedman, Mann–Whitney, Chi-squared, and Fisher tests were used for their analysis.

 The mean of adaptive assertiveness score was significantly different between the the two groups immediately (P=0.002) and 1 month after the intervention (P=0.025). The aggressive assertiveness scores were not significantly different immediately, 1 and 3 months after the intervention (P>0.05), but the results of Friedman test showed a statistically significant decrease in the aggressive assertiveness scores compared to its baseline score (P=0.002).

 The assertiveness training program increased adaptive assertiveness and decreased aggressive assertiveness in nurses. Relevant authorities can design continuous and useful assertiveness training programs to promot this valuable skill in nurses.

 Health literacy is the capacity of a person to obtain, process, and understand basic health information for appropriate health decision making. Self-efficacy is the assurance that is felt about a particular activity which maintains and promotes effective health behaviors. 

 The purpose of this study is to evaluate the relationship between health literacy and self-efficacy in the elderly people.

 This descriptive-correlational study with cross-sectional design was conducted on 144 elderly living in Ramsar city in 2018 who were selected using a random cluster sampling method. Data collection tools were a demographic form, Self Rated Abilities for Health Practices Scale, and Health Literacy for Iranian Adults completed by the researcher after obtaining informed consent from the participants. Data were analyzed in SPSS v.16 software using correlation test, independent t-test, chi-square test, and Fisher’s exact test.

 Most of participants were female (59%), married (86.8%), housekeeper (52.8%) and high school dropouts (35.4%), and moderate financial status (61.8%) with a mean age of 68.75±2.12 years. Pearson correlation test results showed a significant relationship between health literacy and self-efficacy of the elderly (P=0.0001).

 Considering the role of health literacy in increasing the self-efficacy of the elderly, healthcare system policymakers need to pay attention to the issue of health literacy in health system planning.

 Studies have shown that metal nanoparticles are highly active and exhibits remarkable bactericidal activity against a wide range of bacteria.

 The aim of this study was to examine the antibacterial activity of zinc oxide nanoparticles against standard strains of Pseudomonas aeruginosa and Staphylococcus aureus and their isolates in food products.

 This experimental study was conducted on the two pathogenic bacteria and their two standard strains. Zinc oxide nanoparticles were prepared from zeolite and their amount was determined using the XRF analyzer. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were measured using disk diffusion method .

The MIC value of zinc oxide nanoparticles was 4 mg/mL for standard strain and isolate of pseudomonas aeruginosa and 2 mg/mL for standard strain and isolate of staphylococcus aureus. The MBC values for standard strain and isolate of pseudomonas aeruginosa were 16 and 8 mg/mL, respectively, while for the standard strain and isolate of Staphylococcus aureus it was reported 8 mg/mL.

 Staphylococcus aureus is more sensitive to zinc oxide nanoparticles that pseudomonas aeruginosa.

 Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of reproductive age which can cause many problems such as hyperandrogenic symptoms and fertility problems.

 The present study aimed to determine the relationship of mindfulness with hyperandrogenic symptoms and demographic and fertility factors in women with PCOS.

 This descriptive correlational study was conducted on 181 women with PCOS referred to Firoozabadi and Firoozgar hospitals in Tehran, Iran who were selected using a continuous sampling method and based on inclusion criteria from June 2018 to August 2019. Data were collected using a demographic/fertility form, the modified Ferriman-Gallwey Scale, Ludwig Hair Loss Scale, and Mindfulness Attention Awareness Scale (MAAS). Data were analyzed using independent t-test, one-way ANOVA, Kruskal-Wallis test, Pearson correlation test, and multiple linear regression analysis.

 The mean MAAS score of women was 68.61±9.88 and was significantly correlated with age (P=0.01), wife’s education (P=0.001), wife’s occupation (P=0.005), economic status (P=0.02), husband satisfaction with wife’s body and appearance (P=0.02), body mass index (P=0.01), and duration of marriage (P<0.001). According to the multiple linear regression model, the duration of marriage could predict 22% of the variance in overall MAAS score.

 Mindfulness is associated with some demographic variables, among which the marriage is its predictor. It is recommended to pay attention to the reported variables in preparation of counseling or educational programs, along with other treatments, for women with PCOS.

Today, along with the relative expansion of public health around the world, various diseases such as AIDS, malaria, etc. are increasing in human societies. In this regard, the pharmaceutical industry is one of the most important industries that should be supported so that the inventors of new drugs have enough motivation to produce more effective drugs. On the other hand, the undeniable benefits of supporting pharmaceutical inventions pose a serious threat to developing and less developed countries, and may endanger the public health of these societies. In such situation, we should know which of these two principles is preferable to other and should be given priority: Public health as a basic human right or protection of pharmaceutical patents as an exclusive right of its owners? One of the most important issues discussed directly and indirectly in the World Trade Organization is ”public health”, especially the drug trade and the protection of pharmaceutical patents, and this organization has always protected the rights of drug inventors to maintain a balance between public health and freedom of access to medicine. Therefore, any legal system that wants to join this organization may face problems due to these two issues. This study aims to investigate the conditions and challenges of supporting pharmaceutical patents in legal systems in case of accession to the World Trade Organization.

Family is the most important social group, and the survival of society depends on the survival of the family and its survival depends on legitimate parentage and legal ties. Therefore, the issue of proving the parentage is one of the most sensitive issues in the Islamic law and the legislator has tried to preserve it by enacting laws. From the beginning of Islam until now, in Imami jurisprudence and consequently in the civil law, the rule of marriage presumption has been used as a legal evidence to prove the parentage. However, with the widespread development of genetic science and laboratory sciences, genetic tests are used to determine the parentage. Since the Iranian Civil Code does not explicitly mention the ways of proving parentage, and there are disagreements between jurists and jurisprudents on the authority of such tests to prove parentage, these new medical methods have posed various challenges to jurisprudential rules. This study, using jurisprudential and legal sources, aimed to investigate the value and position of genetic tests in proving legal parentage to determine whether the legitimate parentage can be proved based on them in Iranian law or not. The results indicated that genetic testing cannot be considered independently for proving legitimate parentage. These tests, despite their high scientific certainty and validity, can only establish a blood relationship between people. A legitimate parentage is a legal relationship, in addition to being a blood relationship, and without the three conditions of marriage presumption law, genetic testing cannot be relied on to prove it. However, these tests can be helpful in proving some claims, such as identifying unidentified corpses, studying the organ damages caused by air accidents or explosions, and creating a genetic database of criminals.

Primary Ciliary Dyskinesia (PCD) and Kartagener Syndrome (KS) are rare genetic disorders. PCD occurs in patients with recurrent sino-pulmonary infection, dextrocardia, chronic vasomotor rhinitis, and bronchiectasis. This study reports a rare case of KS for having further awareness of this disease. According to this study, this disease should be considered in patients with recurrent respiratory infections, because early diagnosis and timely treatment of these patients can lead to reduced irreversible complications and increased life expectancy.